Pepsin enzymes belonging to this category of proteolytic enzymes are involved in the breakdown of proteins into peptides and amino acids. The pepsin enzyme serves to break down complex protein molecules, such as those found in meat and eggs, into a simpler molecule of peptone. The pepsin enzyme also breaks the peptide bond between amino acids and hydrophobic side chains in the center of the polypeptide. Thus, it converts long polypeptides into short polypeptides. Pepsin enzyme can function in an acidic environment with a pH level of 1.5-2. Pepsin requires an optimum temperature range of 37 degrees Celsius to 42 degrees Celsius (ideal temperature in the human body). Meanwhile, HCl serves to acidify food, as an antiseptic and disinfectant. In addition, HCl also acidifies pepsinogen into pepsin. If you need peptides, you can visit our website to get Australian Peptides.
Although the presence of enzymes is not visible, its function for the body is very important. Disorders or deficiencies of one of the digestive enzymes will cause the digestive system to be less than optimal. Similarly, if our body deficiency or excess pepsin enzyme, will arise some symptoms that interfere with the digestive system, among others:
– Stomach ulcers. Occurs when the amount of hydrochloric acid and enzyme pepsin excess and disrupt the digestive tract mechanism, and erode the protective mucosal wall of the stomach. Patients with ulcers are known to have an imbalance between hydrochloric acid and pepsin, as well as the inability of the gastrointestinal tract to protect themselves from harsh substances. Serious symptoms that arise usually such as nausea, vomiting, loss of appetite, to bleeding in the stomach.
– The enzyme pepsin serves to help convert proteins into amino acids. So the deficiency of pepsin enzymes will certainly disrupt the process and eventually, the absorption of nutrients from food will be disrupted.
Deficiency of pepsin enzymes and other enzymes will lead to metabolic disorders. In principle, treatment for diseases caused by enzyme deficiency is to reduce or eliminate intake of foods and drugs that can not be digested properly. In addition, replacement of missing or inactive enzymes can also be done. And lastly, remove toxic products from metabolism that accumulate due to metabolic disorders.